RNase A (Ribonuclease A) is a bovine pancreatic endoribonuclease that cleaves single-stranded RNA. It catalyzes the cleavage of the phosphodiester bond between the 5’-ribose of a nucleotide and the phosphate group attached to the 3’-ribose of an adjacent pyrimidine nucleotide. This cleavage forms a 2’, 3’-cyclic phosphate, which is then hydrolysed to the corresponding 3’-nucleoside phosphate.
Small single-chain polypeptide: 124 residues, ~13.7 kDa.
Avoids the use of co-factors and divalent cations.
High specific activity: more than 100 Kunitz units per mg protein.
High Quality: free of DNase, Proteinase or exonuclease contamination.
Time-saving protocol: avoids the RNAse heat step before use.
Risk-free: product covered by our Quality 100% Guarantee.
