DNase DNase I is a recombinant endonuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, to release di-, tri- and oligonucleotide products (on average producing tetranucleotides) with 5’-phosphorylated and 3’-hydroxylated ends.
It acts on single-stranded DNA, double-stranded DNA, RNA-DNA hybrids and chromatin. DNase I requires bivalent cations (Mg2⁺ and Ca2⁺) for maximal activity.
Recombinant: bovine Pancreatic, purified from E. coli (29 kDa monomer).
High specific activity: more than 2,000 Kunitz units per mg protein.
High Quality: free of RNase and Proteinase contamination.
Complete solution: supplied with 10x Reaction Buffer.
Risk-free: product covered by our Quality 100% Guarantee.
