The kit offers a pure, concentrated and rapid simultaneous purification of Circulating DNA from cell–free samples such as serum and plasma (1 mL). The cell-free DNA in plasma and serum is known to be highly fragmented 50 – 1,000 bp. The degree of fragmentation depends on several parameters like origin DNA (fetal, tumor, microbial DNA), health of the donor blood, blood sampling procedure and handling of the sample.
The kit uses HigherPurity™ breakthrough technology based in nucleic acid ability to bind silica in the presence of high concentrations of chaotropic salts. For this, it is used a special columns designed for high recovery, especially of fragmented DNA in a range 100 – 1,000 bp and optimized Binding Buffer.
For more details, please follow https://lifescience.canvaxbiotech.com/product/higherpurity-circulating-dna-purification-kit/