Human GRB2 (Growth Factor Receptor-Bound Protein 2), 6xHis tag

Manufacturer: Canvax
Availability: in stock 0 item(s)
Product Code: P2181959
SKU: PR0343
UOM: 100 μg

High quality Recombinant Protein with proven performance in ELISA, WB, Ab Production or Protein array

Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

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