5-hydroxytryptamine (Serotonin) Receptor 1D

Manufacturer: Canvax
Availability: in stock 0 item(s)
Product Code: P21251993
SKU: G0613-Plus
UOM: 15 µL (12-well plate) + 0.2 mL

ExpressMAX™ Expression-ready Human GPCR ORF Clone

GPCR for serotonin, found in nociceptors throughout the body. The anti-migraine action of “triptan” Drugs involves the activation of serotonin subtype 1D (HT1D) Receptors expressed on “pain-responsive” trigeminal primary afferents. HT1D Receptors are present in a similar subpopulation of trigeminal and dorsal root ganglia neurons and in the central terminals of primary afferents.

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