ExpressMAX™ Expression-ready Human GPCR ORF Clone
It belongs to the GPCR 1 family and functions as a Receptor for Angiotensin II. It is an integral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla and atretic ovary. It has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in the gene has been associated with X-linked mental retardation.
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