Apelin Receptor

Manufacturer: Canvax
Availability: in stock 0 item(s)
Product Code: P21312006
SKU: G0511-Plus
UOM: 15 µL (12-well plate) + 0.2 mL

ExpressMAX™ Expression-ready Human GPCR ORF Clone

Apelin Receptor (APLNR, APJ) is a GPCR with considerable sequence homology to the angiotensin Receptor, which is actually an apelin Receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. Its predominant endogenous ligands are apelin-36, apelin-13 and [Pyr1]-apelin-13. APLNR Receptor and apelin peptides act as mediators of cardiovascular and Central Nervous System functions, fluid homeostasis, adipocyte endocrine secretion, glucose metabolism, in embryonic and tumor angiogenesis and as a HIV-1 co-receptor.

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