ExpressMAX™ Expression-ready Human GPCR ORF Clones
It is a Receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. This Receptor, encoded by the gene CCR2, mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. The gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
For more details, please follow https://lifescience.canvaxbiotech.com/product/ccr2-expression-ready-gpcr-orf-clones/
