Product name: IRF2 (5F2) Monoclonal Antibody
Applications: WB, IF(ICC)
Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Host: Rabbit
Source: Recombinant human IRF2 protein, around C-terminal 100aa.
Clonality: Monoclonal
Clone: #5F2
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage buffer: Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage condition: Store at -20°C for 12 months
TARGET
Gene ID: 3660
Swiss Prot: P14316
Synonyms: IRF-2; Interferon regulatory factor 2; IRF2
Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
*Image title: Human lung lysates probed with IRF2 (5F2) Monoclonal Antibody (bsm-52115R) at 1:1000 overnight at 4˚C. Followed by a conjugated secondary antibody.
For more details, please follow https://www.biossusa.com/products/bsm-52115r
